In this lesson, you will analyze human karyotypes to determine if medical. As a current student on this bumpy collegiate pathway, i stumbled upon course hero, where i can find study resources for nearly all my courses, get online help from tutors 247, and even share my old projects, papers, and lecture notes with other students. Karyotyping is the process of pairing and ordering all the chromosomes of an organism, which gives a genome wide idea of any individuals chromosomes. The chronic myeloid leukemia karyotype has one extralong chromosome 9 and one very short chromosome 22. Yeah, reading need will not unaccompanied make you have any favourite activity.
Its a bit harder than the u of a one, but there is a hints option if students get stuck. Karyotyping lab karyotyping labchapters 9, 11 academic biology 10dr. One normal male, one normal female, two different disorders of your choice out of the four. This ordering and pairing of chromosomes is called a karyotype. University of arizona karyotyping activity in this activity, you will use a computer model to look at chromosomes and prepare a karyotype. What is the haploid chromosome number for your karyotype your karyotype may have 2 answers here. Karyotype lab starting with a we cut and paste the photo to get this actually a technician uses scissors to cut and paste the chromosomes on a sheet of paper. A karyotype is a visual representation of an individuals chromosomes arranged in a specific way. For each couple, you must construct and analyze a karyotype. Example of a karyotype after staining and pairing based on size and structure. Download file pdf human karyotyping activity answer key human karyotyping activity answer key human karyotyping activity answer key other results for answer key for karyotyping activity.
You will be arranging chromosomes into a completed karyotype, and interpreting your findings just as if you were working in a genetic analysis program at a hospital or clinic. Karyotype analysis flashcards and study sets quizlet. Karyotype chromosome lab activity activities, edwards. Click karyotyping lab to view what your karyotype should look like. A karyotype is a photograph of all of an organisms chromosomes. Summarize how a karyotype is made in 5 major steps. Start the sorting processes by clicking the start button. Using the attached sheets, complete four different karyotypes. Lab technicians compile karyotypes and then use a specific notation to characterize the karyotype. Cancer is a large, overwhelming, and sometimes frightening diagnosis. Students are given a set of chromosomes that may be from a male or a female and build a karyotype to find out. Standardized staining methods are employed in the preparation of karyotypes, which helps in revealing the structural features of each chromosome. Can result from an extra chromosome or defective genes karyotype a photograph of a cells chromosomes arranged in pairs according to size the nucleus chromosomes genes deoxyribonucleic acid dna. Thank you so much for being part of the betterlesson community.
Usually, this is done by a genetic counselor trying to determine if the person has a genetic abnormality. Diagnosing chromosome disorders, haspi medical biology lab 17 names. The human male determines the sex of all of his offspring. Karyotyping practice scientists have developed several different tools and techniques for studying chromosomes, genes and base pairs in humans and other organisms. The purpose of this activity is to introduce you to chromosomal karyotyping. Karyotype chromosome lab activity by beverly biology tpt. Occasionally chromosomal material is lost or rearranged during the formation of gametes or during cell division of the early embryo. Student handout creating a karyotype that contains the directions and sample karyotype image. Karyotyping activity in this activity, you will use a computer model to look at chromosomes and prepare a karyotype. Bring me your progress report if you did not have it today. Karyotyping chromosomes involves classifying and organizing them according to the arrangement, number, size, shape, or other characteristics of the chromosomes. You will diagnose patients for abnormalities and learn the correct notation for characterizing karyotypes. Karyotype and idiogram ppt karyotype, idiogram and its significance ppt what is karyotype. A karyotype can show prospective parents whether they have certain abnormalities that could be passed on to their offspring, or it may be used to learn the cause of a childs disability.
View karyotyping web activity from aa 1biology hsscience unit. They can tell us everything from the likelihood that an unborn baby will have a genetic disorder to whether a person will be male or female. Determine the sex of an individual from a karyotype. When their karyotype is finished they will be able to identify 1 of 3 different karyoty. Karyotyping activity introduction this exercise is a simulation of human karyotyping using digital images of chromosomes from actual human genetic studies.
Choose from 49 different sets of karyotype analysis flashcards on quizlet. Chromosome analysis national human genome research. The purpose of this activity is to analyze a simulated karyotype, called an ideogram, in order to identify the genetic composition of both a normal cell and a cancerous cell. Patient c answer key word and pdf format key words. You will be creating a karyotype of an individual using simulated human chromosomes.
This notation includes the total number of chromosomes, the sex chromosomes, and any extra or. How could you determine if your karyotype was male or female. To make a chromosome spread, one blocks the progression of mitosis at metaphase where chromosomes. Next, take the students to the computer lab and go to the website the biology. When you have completed the karyotype, follow the instructions to interpret the karyotype. Karyotyping activity the biology project university of arizona. Half of the kids will get boys and half the kids will get girls, but it will be a surprise. All books are in clear copy here, and all files are secure so dont worry about it. Karyotyping web activity biology hsscience unit 07. Chromosome 21 actually contains fewer base pairs, and is therefore shorter, than chromosome 22. Displaying all worksheets related to karyotype activity. The karyotype za karyotype is a pattern or picture of chromosomes.
Human karyotyping activity normal karyotype word format pdf format. How many times a year are karyotyping analysis done. Such changes, primarily the result of nondisjunction or translocation, are so severe that the pregnancy ends in miscarriage or fertilization does not occur at all. Scientists often analyze chromosomes in prenatal testing and in diagnosing specific diseases. It should be a numberthe total number of chromosomes and then xx or xy to show male or femalefor example, a normal. This notation includes the total number of chromosomes, the sex chromosomes, and any extra or missing autosomal. Worksheets are lesson 2 analyzing chromosomes, 14, karyotyping activity, human karyotyping lab, ccut n paste karyotyping activityut n paste karyotyping, biology 1 work i selected answers, appendix a human karyotyping work, karyotype activity answers.
When their karyotype is finished they will be able to identify 1 of 3 different karyotype disorders. Karyotype station activities welcome to science lessons. This important model can be broken down into four main ideas. Karyotyping helps doctors diagnose and treat genetic disorders. The following procedure is utilized to perform this laboratory experience. What type of cell samples are used for karyotyping. Karyotype curiosities determining different karyotypes when geneticists want to look at a persons chromosomes, they make a karyotype. In this activity, you will use a computer model to look at chromosomes and prepare a karyotype. Now go to the following site and answer the following questions.
Which sex chromosomes are present in the karyotype you prepared. In preparation of this activity, each student will need the following supplies. Virtual karyotyping lab san juan unified school district. The remainder of the karyotype is that of a normal female. This was not known in 1961 when the denver system was established. Reading this karyotyping virtual lab activity answer sheet will pay for you more than people admire. Students then diagnose the chromosomal aneuploidy based on the karyotype, list the symptoms associated with the disorder, and discuss the implications of the diagnosis. Analyze the karyotype and write a diagnosis in the box provided. Get human karyotyping activity lab 14 answers pdf file for free from our online library pdf file. This exercise is a simulation of human karyotyping using digital images of chromosomes from actual human genetic studies. Identify pairs of homologous chromosomes by length, centromere position, and banding patterns. Doctors use a normal human karyotype and compare it to the karyotype of a patient to determine if there are abnormalities. This activity is targeted at undergraduates in a nonmajors genetics course.
The purpose of karyotype analysis is to look at the gross anatomical structures of the chromosomes of an individual. Chromosome analysis national dna day april 25, 2005. You will be arranging chromosomes into a completed karyotype and interpreting your findings jus. A karyotype is a picture of chromosomes that have been organized in homologous pairs from. Karyotype virtual lab in this virtual lab from university of utah, students pair up the chromosomes on the left with their homologous pair on the right. It will guide to know more than the people staring at you. Complete the web activity to practice completing and analyzing. Karyotyping activity the biology project lab technicians compile karyotypes and then use a specific notation to characterize the karyotype. What notation would you use to characterize patient as karyotype. Karyotype analysis activity the american biology teacher. Nov 01, 2016 this feature is not available right now. This karyotype analysis activity was designed for undergraduates in a nonmajors genetics course.
To create karyotypes, chromosomes from a cell are stained and photographed. Acces pdf karyotyping virtual lab activity answer sheet karyotyping virtual lab activity answer sheet chromosomes and karyotypes explore chromosomes and karyotypes with the amoeba sisters. Wastewater treatment provides for authentic inquirybased experiences in the lab and beyond. How do two physically healthy parents produce a child with down syndrome and a second child with cri du chat syndrome. Scientists have developed several different tools and techniques for studying chromosomes, genes and base pairs in humans and other organisms. Analysis questions 1 how many autosomes any chromosome that that is not a sex chromosome are in a normal human karyotype. Sep 04, 2019 karyotype virtual lab in this virtual lab from university of utah, students pair up the chromosomes on the left with their homologous pair on the right. Very studentcentered and allows the teacher to be a coach rather then a the speaker. This lab based activity allows students to use genetics knowledge to understand how to use and create a karyotype and pedigree. Comets living environment laboratory manual, 2007, sout h lewis high school, turin, new york 473.
You will be arranging chromosomes into a completed karyotype. What is the name of the dye they use to color the chromosomes so they can be seen. We will use your feedback to improve the experience for every teacher on. Karyotyping activity this exercise is a simulation of human karyotyping using digital images of chromosomes from actual human genetic studies. What is the diploid chromosome number for your karyotype. Acces pdf karyotyping virtual lab activity answer sheet. Biologists utilize a technique called a chromosome spread followed by a karyotype or karyogram. Karyotyping and genetic disorders autosomal disorders disorders involving the other 22 pairs of chromosomes. Even now, there are many sources to learning, reading a compilation nevertheless becomes the. Pdf karyotyping lab key north allegheny karyotyping lab karyotyping lab chapters 9, 11 academic biology 10dr. This classroom activity is based on a constructivist learning design and engages students in physically constructing a karyotype of three mock patients. Karyotypes can also reveal the gender of a fetus or test for. Karyotyping lab karyotyping lab chapters 9, 11 academic biology 10dr.
The concept is to big that we forget that cancer starts small, at the cellular level. The figure on the back of this page is a representation of gbanded chromosomes only 1 chromosome from each homologous pair is represented. Introduction mendels model of inheritance is the basis for modern genetics. Largescale genomic rearrangements result in genetic abnormalities. Answer karyotype sheet 4the mantle cell lymphoma karyotype has one altered chromosome 11 and one.
Students will cutout unmatched chromosomes and paste them next to their identical homologous mate. Chromosome spread scissors karyotype analysis worksheet tape ruler. Homologous pairs can be determined by centromere placement, equal length of top and bottom arms as well as similar band placement on each arm. Arrange the chromosomes from largest smallest and place the chromosomes in their homologous pairs homo same. Analyze and predict whether an individual will have a genetic disorder. Once your chromosomes are all cut out and included in the karyotypes, answer the questions and complete the lab. Permission is granted for notforprofit educational use by certified teachers. This is a great activity where students complete a paper karyotype so they can diagnose a chromosome disorder. Other results for answer key for karyotyping activity. Answer the following questions before turning in your lab. Karyotyping project learning resources and technology services. Additional laboratory minutes may be granted for work above and beyond the four required karyotypes. We would like to show you a description here but the site wont allow us.
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